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Background Osteoporosis is a common disorder with a strong genetic component. One way in which the genetic component . Sainz, J., Van Tornout, J. M., Sayre, J., Kaufman, F., Gilsanz, V. (1999). Association of Collagen Type 1 {alpha}1 Gene . M. (2002). Osteoprotegerin Gene Polymorphism and the Risk of Osteoporosis and Vascular Disease. J. Clin. Endocrinol. . Beavan, S., Prentice, A., Dibba, B., Yan, L., Cooper, C., Ralston, S. H. (1998). Polymorphism of the Collagen Type I{ . Pluijm, S M F, van Essen, H W, Bravenboer, N, Uitterlinden, A G, Smit, J H, Pols, H A P, Lips, P (2004). Collagen type I . 2005). Contribution of the Collagen I {alpha}1 and Vitamin D Receptor Genes to the Risk of Hip Fracture in Elderly Women . Collagen Type I {alpha}1 Gene Sp1 Polymorphism in Premenopausal Women with Primary Osteoporosis: Improved Detection of . Collagen Type I{alpha}1 Gene to Bone Density and the Risk of Osteoporotic Fractures in Postmenopausal Women .NEJM — Relation of Alleles of the Collagen Type Ialpha1 Gene to Bone Density .

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